A comparative illustration of foundational ontologies : BORO and UFO

This paper investigates the differences that exist between a 3D and a 4D ontology. We examine these differences by comparing both ontologies through the metaphysical choices each ontology makes and explore the composing characteristics that define them. More specifically, the differences between the ontologies were illustrated through several modeling fragments that were derived from a modeling case presented at the 5thOntoCom workshop. Each of these modeling fragments focused on the metaphysical choices that the ontologies make –Essence and Identity, Relationships and Time. These comparisons highlighted the different ontological approaches and structures that exist between the ontologies. Moreover, depending on the ontology, the resulting conceptual model could differ substantially, confirming the impact and importance of the choice of a certain ontology. The observed differences between both ontologies eventually led us to formulate three discussion points that question the applicability of certain metaphysical choices in certain circumstances, and that can serve as a basis for future discussion or future research studies in the domain of ODCM

Early identification of potential distributed ledger technology business cases using e3value models

Many Distributed Ledger Technology (DLT) projects end prematurely without reaping benefits. Previous research has indicated a lack of sustainable business cases for many Blockchain projects. A successful project has a disruptive impact on the business ecosystem. The paper investigates how e3value modeling can contribute to identifying the potential success of DLT implementation. Using insights from a first DLT case-study, an abstract e3value model fragment is defined that indicates potential success. As a test, the e3value model fragment is subsequently applied to a second case-study that is currently being implemented as a DLT-based platform. The paper concludes by reflecting on how an e3value model can provide evidence of meeting the requirements for building a sustainable DLT business case

Exploratory outlier detection for acceleromyographic neuromuscular monitoring : Machine learning approach

Funding Information: This research was funded by the Flanders Innovation and Entrepreneurship Fund, the Willy Gepts Fund for Scientific Research, and the Society for Anesthesia and Resuscitation of Belgium (SARB). Publisher Copyright: © Michaël Verdonck, Hugo Carvalho, Johan Berghmans, Patrice Forget, Jan Poelaert. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 06.06.2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.Peer reviewedPublisher PD

A survey on the availability, usage and perception of neuromuscular monitors in Europe

Funding This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. This research was funded by the Flanders Innovation and Entrepreneurship Fund (VLAIO), the Willy Gepts Fund for Scientific Research, the Society for Anesthesia and Resuscitation of Belgium (BeSARPP), and the Vrije Universiteit Brussel (VUB).Peer reviewedPostprin

An exploratory analysis on the comprehension of 3D and 4D ontology-driven conceptual models

In this paper, we perform an exploratory analysis to investigate the impact of adopting a 3D and a 4D foundational ontology on the quality of a conceptual model. More specifically, we determine the impact of the metaphysical characteristics of an ontology on the comprehension and understandability of the ontology-driven models by its users. The contributions of this research are: (1) while much effort in ODCM has been devoted into the syntactic and semantic aspects of models for improving their overall quality, this research focuses on the pragmatic aspect of a model; and (2) since little empirical research has yet been performed in this area, we formulated several hypotheses that are derived from the results and observations from our exploratory analysis. These hypotheses can then serve as a testing ground for future empirical research in order to investigate the fundamental differences between 3D and 4D ontology-driven models

An ontological analysis framework for domain-specific modeling languages

This article describes how domain-specific modeling languages (DSML) are developed to specifically model certain domains and their phenomena. Over the last 15 years, different kinds of DSMLs have been ontologically analyzed to improve their ontological expressiveness. However, the term ‘ontological analyses’ encompasses a great variety of different purposes, techniques or methods, and can thus be performed in many different ways without maintaining clear differentiation. Therefore, in this article, the authors aim to structure the process of conducting an ontological analysis, and offers guidelines in the form of descriptive patterns for analyzing a DSML. With the help of this framework, a researcher with a specific purpose can recognize the required patterns and types of methods that can be followed in order to successfully conduct an ontological analysis and achieve the intended purpose

Insights on the use and application of ontology and conceptual modeling languages in ontology-driven conceptual modeling

In this paper, we critically survey the existing literature in ontology-driven conceptual modeling in order to identify the kind of research that has been performed over the years and establish its current state of the art by describing the use and the application of ontologies in mapping phenomena to models. We are interested if there exist any connections between representing kinds of phenomena with certain ontologies and conceptual modeling languages. To understand and identify any gaps and research opportunities, our literature study is conducted in the form of a systematic mapping review, which aims at structuring and classifying the area that is being investigated. Our results indicate that there are several research gaps that should be addressed, which we translated into several future research opportunities

Development and validation of an android-based application for anaesthesia neuromuscular monitoring

Quantitative neuromuscular block (NMB) assessment is an internationally recognised necessity in anesthesia care whenever neuromuscular blocking agents are administered. Despite this, the incidence of residual neuromuscular block and its associated major respiratory morbidity and mortality remain unacceptably high considering its preventable nature. Recent surveys show that quantitative NMB assessment is not consistently employed by anesthesiologists. Availability, price and practical concerns are some of the factors determining this phenomenon. Clinically assess and validate an Android cell phone application conceived specifically for NMB Monitoring in the anesthesia setting. Twenty-two adult ASA I to III patients scheduled to undergo elective surgical procedures under general anaesthesia requiring administration of a neuromuscular blocking agent were included. After anaesthesia induction, the grade of neuromuscular block was assessed at multiple independent time-points by paired comparison of the train of four (TOF) Ratios obtained by a Stimpod (TM) accelerometer and the currently developed application. Accelerometric measurements were made at the patient's hand after retrograde supramaximal stimulation of the ipsilateral ulnar nerve. TOF-ratios were subjected to bias analysis with 0.001 as the a priori established clinical significance cut-off. The difference between the two methods averaged 0.0004 (95% limits of agreement: +/- 0.12), with 83.3% of the differences being under 0.05. This average inter-method difference was not significantly different than the a priori hypothesized difference cut-off of 0.001 (p = 0.78). Lin's concordance correlation coefficient and Pearson's correlation were both of 0.98. The custom developed Android application proved accurate for diagnosis of residual neuromuscular block